Vitamin E (α-tocopherol) is a vital antioxidant with antiinflammatory properties, playing a key role in preventing and managing chronic diseases. In Brazil, however, vitamin E intake is often inadequate, raising concerns about potential deficiency within the population. Despite this, there is limited research on the prevalence of vitamin E deficiency, with existing studies showing varying results. Discrepancies may stem from challenges in accurately assessing dietary intake or interpreting deficiency biomarkers. Insufficient vitamin E intake or low body levels could heighten susceptibility to diseases linked to oxidative stress, such as cardiovascular diseases, cancer, and neurodegenerative disorders like Alzheimer’s and Parkinson’s. Given the rising prevalence of chronic diseases in Brazil and the unclear implications of inadequate vitamin E status, deficiency may pose a significant public health concern. Further investigation into vitamin E intake and its role in disease prevention is crucial to understanding its impact on the population’s health.