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Soft-Tissue Sarcomas

  • Santiago A. Lozano-Calderon,
  • Mitchell S. Fourman,
  • Dipak B. Ramkumar

摘要

Soft-tissue sarcomas are rare entities with myriad presentations, characteristics, and prognoses. The diagnosis and management of soft-tissue sarcomas differ by their tissue of origin and their sensitivity to radiation and systemic therapies. While many soft-tissue sarcomas, such as myxofibrosarcoma and liposarcoma, can be managed with preoperative radiotherapy followed by wide excision, entities such as Ewing’s sarcoma can be treated with chemotherapy and radiation alone. This chapter summarizes the differentiating pathologic and radiographic characteristics between types of soft-tissue sarcomas as well as literature-supported diagnostic and treatment strategies. The utility of chemotherapy and immunotherapy in the treatment of soft-tissue sarcoma will be addressed. Finally, currently available prognostic indices and their utility will be discussed.