Ocular infections represent a significant spectrum of conditions impacting visual health, each with distinct etiologies and clinical manifestations. This chapter delves into notable infectious agents such as toxoplasmosis, toxocariasis, syphilis, tuberculosis, cat scratch disease, herpes simplex, cytomegalovirus, and arboviruses. Ocular toxoplasmosis, characterized by retinochoroiditis and potential recurrences, illustrates the complex interplay between congenital and acquired forms of the disease. Toxocariasis highlights the impact of visceral larva migrans, particularly in children, while ocular syphilis showcases a range of presentations from uveitis to retinitis that can arise at various disease stages. Tuberculosis can affect multiple ocular structures, complicating diagnosis, and management. Cat scratch disease manifests through neuroretinitis and multifocal retinitis, adding to the clinical diversity. Furthermore, the herpes simplex and cytomegalovirus infections present unique retinal complications, particularly in immunocompromised patients. The chapter culminates with an overview of arboviral infections, emphasizing their potential ocular implications. Understanding these infections is crucial for effective diagnosis and treatment, ultimately aiming to preserve vision and improve patient outcomes.