Sympathetic Ophthalmia

A rare condition known as sympathetic ophthalmia manifests clinically as diffuse, bilateral, non-necrotizing granulomatous uveitis. It typically happens days, months, or even decades following eye surgery or serious trauma. Granulomatous anterior uveitis is the most common clinical manifestation. Nonetheless, Dalen-Fuchs nodules, which are yellowish-white retinochoroidal lesions, can frequently manifest clinically. Fluorescein angiography is crucial for detecting window defects and blockage in its early stages. The etiology of sympathetic ophthalmia remains unclear. An autoimmune reaction to uveal antigens found in post-trauma has been described by some authors. Treatment includes systemic corticosteroids and systemic immunosuppressive agents. Cataract, glaucoma, and subretinal neovascular membrane are manageable complications. In terms of prognosis, early and vigorous treatment may preserve visual acuity in the sympathizing eye.