The sociology of knowledge is basically concerned with everything that is regarded as knowledge in society. Research in the sociology of knowledge dealing with innovation thus covers a wide range of topics, which are systematically presented here. The chapter, first, clarifies the sociological perspective on knowledge by proposing the basic sociality of all knowledge. Innovation is based on the basic orientation of actions toward the future which are social. It is by way of its social nature that innovations become socially effective. It is on the basis of a social concept of knowledge that the article then deals with exemplary subject areas in which pioneering sociological knowledge research is currently being conducted: (1) the communicative genesis of innovation in space from urban development policy, and (2) innovation phenomena in the context of mediatization research in the fitness field. Finally, it will outline the potentials of recent developments within the sociology of knowledge and research desiderata will be formulated.