This chapter uses Lacanian psychoanalysis to explore the inner dimensions of the horror video games Dead Space (2008, 2023) and Dead Space 2 (2011). Central to this analysis is the interpretation of the zombie-like Necromorphs as representations of the impossible “Real,” embodying both the inescapable materiality of death and the “undead” drive for unattainable wholeness. The chapter further argues that these creatures’ grotesque intrusions into the games’ narrative thematically reflect the severe psychological repercussions of protagonist Isaac Clarke’s refusal to accept the Real-ity of his girlfriend Nicole’s death and his impossible attempt to “save” her. By tracing Isaac’s journey from maladaptive denial to a symbolic confrontation with his loss, the chapter argues that Isaac’s gradual acceptance of Nicole’s absence is mirrored in his successful but not absolute defeat of the Necromorphs. In this way, the story told in Dead Space and Dead Space 2 demonstrates that while the Real (like the Necromorphs, or the tragedy of Nicole’s death) can never be eliminated, human subjects (like Isaac Clarke) can still live meaningful lives by recognizing and accepting the Real-ity of loss for what it is.