Identification of Potential Biomarkers Using Integrative Approach: An Application of ESCC
摘要
This paper presents a consensus-based approach that incorporates three microarray and three RNA-Seq methods for an unbiased and integrative identification of Differentially Expressed Genes (DEGs) as potential biomarkers for critical disease(s). The proposed method has been found to perform satisfactorily on two microarrays and one RNA-Seq datasets for Esophageal Squamous Cell Carcinoma (ESCC). It has been able to identify 9 crucial genes for ESCC.