Arteriopathies

Genetically mediated arteriopathies are a group of conditions characterized by abnormal arterial microarchitecture with resultant deranged anatomic features and arterial function. The abnormalities of the arterial tree affect both the systemic and pulmonary circulations. The most common genetically mediated arteriopathy is Williams syndrome, which is covered in detail in this chapter, along with both Elastin Arteriopathy and Arterial Tortuosity syndrome. These conditions are discussed in-depth, including etiology, clinical manifestations, treatment, and follow-up. Additionally, these arteriopathies serve as representative of other much rarer and less understood conditions with arteriopathy.