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Directed Drug Convection Using Magnetic Nanoparticles as Therapeutic Carriers Meeting the Challenge of Specific Brain Pharmacotherapeutics, Non-ligand-Based Central Nervous System Targeting, Including Magnetic Focusing

  • Drora Samra-Shevy,
  • Babak Kateb,
  • David F. Moore,
  • Vinith Yathindranath,
  • Torsten Hegmann,
  • Donald Miller,
  • Marc Pelletier,
  • Raphael Schiffman

摘要

This chapter, titled “Directed Drug Convection Using Magnetic Nanoparticles,” explores the use of magnetic nanoparticles for precise drug delivery in the central nervous system (CNS). Magnetic nanoparticles can be guided by external magnetic fields, enabling targeted drug delivery within the brain. The chapter covers applications in treating neurological diseases and controlled drug release. While highlighting the potential of magnetic nanoparticles, it addresses considerations like biocompatibility and safety. In summary, this chapter underscores how magnetic nanoparticles enhance CNS pharmacotherapeutics, offering more effective treatments for neurological disorders.