Awareness of the materiality of early modern women’s manuscripts, an area that has been the focus of much recent research, is central to a full understanding of women’s writing in the early modern period. This entry describes the main physical properties of early modern women’s manuscripts, explains how manuscripts were produced, introduces techniques for analyzing manuscript materiality, and indicates some potential directions for future work. The first section focuses on general manuscript features, specifically the manufacture of pens, ink, and paper, handwriting, scribal practice, and the use of watermarks in manuscript analysis. The second section explains the key distinction between manuscript texts copied into prebound paper books and those written out initially on unbound sheets, while the third concentrates on the materiality of early modern women’s letters, an area in which much recent research has taken place. As a whole, the entry shows that a full analysis of manuscript materiality must also involve close reading of the ideas and motivations of the manuscripts’ creators and users.