Scholarlink

This chapter discusses essential methodological considerations for integrating functional magnetic resonance imaging (fMRI) with neuromodulation techniques such as optogenetics, chemogenetics, and fiber photometry. The synergy of these approaches with fMRI provides a robust framework to investigate neural circuit dynamics, neurovascular coupling, and behavior correlates of imaging features in preclinical models. Combining fMRI with these neuromodulatory and recording tools offers a systems-level view of neural activity and the potential to reveal the functional impact of targeted activity on complex brain networks.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Methodological Considerations for fMRI with Optogenetics, Chemogenetics, and Fiber Photometry

  • 实验方案

  • 发表日期：

    2026年

查看全文
  • Sheng Song,
  • Tzu-Hao Harry Chao,
  • Li-Ming Hsu,
  • Randy Nonneman,
  • Tzu-Wen Winnie Wang,
  • Yen-Yu Ian Shih

摘要

This chapter discusses essential methodological considerations for integrating functional magnetic resonance imaging (fMRI) with neuromodulation techniques such as optogenetics, chemogenetics, and fiber photometry. The synergy of these approaches with fMRI provides a robust framework to investigate neural circuit dynamics, neurovascular coupling, and behavior correlates of imaging features in preclinical models. Combining fMRI with these neuromodulatory and recording tools offers a systems-level view of neural activity and the potential to reveal the functional impact of targeted activity on complex brain networks.