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Array comparative genome hybridization, array CGH or aCGH, enable dense interrogation of copy number alterations at specific loci or the entire human genome, and even allele-specific characterization of single-nucleotide polymorphisms (SNPs); they are commonly referred to as oligo-arrays and SNP-arrays, respectively, or chromosomal microarrays in general. Here we present an overview of the state of the field, potential applications, detailed protocols on the use and a troubleshooting guide.

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Array CGH

  • 实验方案

  • 发表日期：

    2026年

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  • Anastasios K. Mitrakos,
  • Eftychia Dimitriadou,
  • Joris R. Vermeesch

摘要

Array comparative genome hybridization, array CGH or aCGH, enable dense interrogation of copy number alterations at specific loci or the entire human genome, and even allele-specific characterization of single-nucleotide polymorphisms (SNPs); they are commonly referred to as oligo-arrays and SNP-arrays, respectively, or chromosomal microarrays in general. Here we present an overview of the state of the field, potential applications, detailed protocols on the use and a troubleshooting guide.