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Chromosome bar codes (CBCs) based on locus-specific probes, i.e., bacterial artificial chromosome (BAC) clones, were widely used in molecular cytogenetics about 20 years ago to identify and characterize chromosomes. In recent years, CBCs have been reintroduced, but now for the characterization of specific chromosomal subregions. Here, we summarize some of these CBCs and highlight some points to consider when setting up CBCs.

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Bar-Coding Is More Actual Than Ever

  • 实验方案

  • 发表日期：

    2026年

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  • Thomas Liehr,
  • Isabel M. Carreira,
  • Joana B. Melo

摘要

Chromosome bar codes (CBCs) based on locus-specific probes, i.e., bacterial artificial chromosome (BAC) clones, were widely used in molecular cytogenetics about 20 years ago to identify and characterize chromosomes. In recent years, CBCs have been reintroduced, but now for the characterization of specific chromosomal subregions. Here, we summarize some of these CBCs and highlight some points to consider when setting up CBCs.