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In recent years, we have seen an explosion of research focused on understanding the intricate mechanisms revolving around enteric glia biology and their role in regulating gastrointestinal function and pathophysiology. This uptake in research has resulted in the development of novel technologies and approaches to study enteric glia. Numerous transgenic animal models have been developed that allow for the selective manipulation of enteric glia in vivo and ex vivo. In this chapter, we will review two transgenic animal models commonly used in glia research and provide detailed methods to implement them experimentally.

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Transgenic Mouse Models to Study Enteric Glia

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  • 发表日期：

    2026年

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  • Wilmarie Morales-Soto

摘要

In recent years, we have seen an explosion of research focused on understanding the intricate mechanisms revolving around enteric glia biology and their role in regulating gastrointestinal function and pathophysiology. This uptake in research has resulted in the development of novel technologies and approaches to study enteric glia. Numerous transgenic animal models have been developed that allow for the selective manipulation of enteric glia in vivo and ex vivo. In this chapter, we will review two transgenic animal models commonly used in glia research and provide detailed methods to implement them experimentally.