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Complex interactions between viruses and host cells are difficult to study via traditional models. Organoids, three-dimensional (3D) tissue-like structures derived from stem cells, have emerged as transformative tools for modeling human tissues and revealing the intricate dynamics of virus–host interactions. This chapter summarizes the relevant applications of organoids in virus–host interaction studies and provides detailed information and experimental procedures for using them to study virus–host interactions.

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Application of Organoids to Investigate Virus–Host Interactions

  • 实验方案

  • 发表日期：

    2025年

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  • Tong Wu,
  • Quan Zhou,
  • Chunfu Zheng,
  • Xiaodong Zou

摘要

Complex interactions between viruses and host cells are difficult to study via traditional models. Organoids, three-dimensional (3D) tissue-like structures derived from stem cells, have emerged as transformative tools for modeling human tissues and revealing the intricate dynamics of virus–host interactions. This chapter summarizes the relevant applications of organoids in virus–host interaction studies and provides detailed information and experimental procedures for using them to study virus–host interactions.