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The metabolites present in seminal plasma are products of several functions in spermatozoa, such as energy production, motility, protection, pH control, and regulation of metabolic activity, among others. The use of metabolomics tools to search for biomarkers in human and animal andrology has grown in recent years and has proven to be highly efficient. With the present technique, it was possible to identify more than 1286 molecules in seminal plasma and more than 1393 molecules in boars’ sperm.

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Molecular Determinants in Seminal Plasma and Spermatozoa: Nontargeted Metabolomics

  • 实验方案

  • 发表日期：

    2025年

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  • André Furugen Cesar de Andrade,
  • Mariana Andrade Torres,
  • Heidge Fukumasu,
  • Arina Lázaro Rochetti,
  • Simone Maria Massami Kitamura Martins,
  • Francisco José de Novais,
  • Christina Ramirez,
  • Bruce Cooper

摘要

The metabolites present in seminal plasma are products of several functions in spermatozoa, such as energy production, motility, protection, pH control, and regulation of metabolic activity, among others. The use of metabolomics tools to search for biomarkers in human and animal andrology has grown in recent years and has proven to be highly efficient. With the present technique, it was possible to identify more than 1286 molecules in seminal plasma and more than 1393 molecules in boars’ sperm.