The evaluation of the efficacy of sports supplements on performance metrics has become significant in athletic training and competition. Various sports supplements (SS) and foods have been classified based on their chemical nature and functionality. These SS affect many aspects of performance metrics, including physical attributes, physiological responses, tactical performances, technical skills, and recovery from injuries. Several studies confirm the remarkable impact of SS such as β-alanine, L- arginine, branched-chain amino acids, caffeine, L-carnitine, collagen, creatine, curcumin, dietary nitrate, fruit-derived polyphenols, glycerol, protein supplement, and whey protein supplement on performance metrics of sports. They have been found to substantially enhance endurance, strength, agility, power, speed, fitness, and healing in athletes. The methods of evaluation to determine the effectiveness of sports supplements on performance have been discussed, along with their influence on athletic accomplishments and performance. It provides an evidence-based insight as the methods and results presented here clearly indicate a positive outcome in terms of sustained energy levels, reduced fatigue, better tactical execution, and optimized performance in sportspersons.