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MiRNA therapeutics for treatment of cardiovascular disease face several problems with delivery. Encapsulation of miRNA therapeutics in cationic liposomes has shown potential to address many of these concerns with miRNA therapeutic delivery. Here we outline the formulation and characterization of cationic liposomes, capable of encapsulating and delivering miRNA therapeutics to AC16 cardiomyocyte cell lines, by microfluidics.

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Cationic Liposome Formulation by Microfluidics for miRNA Delivery

  • 实验方案

  • 发表日期：

    2025年

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  • Matthew Reily-Bell,
  • Rishi Shah

摘要

MiRNA therapeutics for treatment of cardiovascular disease face several problems with delivery. Encapsulation of miRNA therapeutics in cationic liposomes has shown potential to address many of these concerns with miRNA therapeutic delivery. Here we outline the formulation and characterization of cationic liposomes, capable of encapsulating and delivering miRNA therapeutics to AC16 cardiomyocyte cell lines, by microfluidics.