The global demand for plant-based proteins is increasing, driven by consumer interest in healthier and more sustainable diets. This chapter provides an overview of the US regulations and international testing standards related to plant-based proteins, focusing on market approval/recognition, labeling requirements, testing standards resources, and the relationship between regulations and testing standards. The information can help industry, academia, and consumers understand the requirements for introducing new plant-based protein products to the market or developing new applications for the existing protein ingredients.