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Pop-Out Myocardial Infarction Induction in Mice

  • Bingyan J. Wang,
  • Hina W. Chaudhry

摘要

Myocardial infarction (MI) in mice is a widely used surgical model in preclinical cardiac repair studies to recapitulate human cardiovascular ischemic disease. Induction of reproducible infarct size is crucial for quantitative and analytical purpose. Here we describe a quick and reliable method to induce consistent infarct size in mice in less than a minute.