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Analysis of Nanoparticles’ Effects on Drug-Induced Psoriasis

  • Ankit Shah,
  • Chelsea Sanders,
  • Simone Difilippantonio,
  • Elijah Edmondson,
  • Marina A. Dobrovolskaia

摘要

Psoriasis, an auto-inflammatory disorder, has major manifestations in the skin but can affect other organs. Currently, this condition has no cure, and the treatments include anti-inflammatory medications. Nanoparticles are widely used for drug delivery and have found successful applications in therapy for cancer and infectious diseases. Nanoparticles can also be used to deliver anti-inflammatory drugs to sites of inflammation. Moreover, some nanotechnology platforms possess intrinsic anti-inflammatory properties and may benefit the therapy of inflammation-driven disorders. Herein, we present a protocol to study nanotechnology concepts’ anti-inflammatory properties in a chemically-induced psoriasis model.