Recent Advances in Clinical Applications of P300 and MMN

Event-related potentials (ERP), in particular P300 and MMN, have been used for decades in clinical research, but hardly in clinical practice. This chapter provides an overview of recent clinical ERP studies with P300 and MMN as primary components. Due to the (non-)availability of recent studies, this review is restricted to traumatic brain injury, Parkinson’s disease, attention deficit/hyperactivity disorder, borderline personality disorder, schizophrenia, depression, alcohol use disorder, and, in particular, dementia/mild cognitive impairment. The main findings are summarized at the end of each chapter. In the general discussion, possibilities for the clinical application of ERPs as derived from the current research are summarized, and strategies to promote the use of ERPs in clinical practice are suggested.