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Isolation of Human Villous Cytotrophoblastic Cells from Term Placenta for Transfection

  • Caroline Toudic,
  • Benoit Barbeau

摘要

Isolation of villous cytotrophoblastic cells (vCTBs) from placental tissue provides the possibility of studying differentiation of these cells as well as their function. We describe herein a protocol, in which term placentas are used to isolate a population of vCTB in high quantities. These cells are subsequently used to transfect siRNA through microporation and thereby to achieve efficient silencing of targeted genes.