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GRAMM Web Server for Protein Docking

  • Amar Singh,
  • Matthew M. Copeland,
  • Petras J. Kundrotas,
  • Ilya A. Vakser

摘要

Prediction of the structure of protein complexes by docking methods is a well-established research field. The intermolecular energy landscapes in protein–protein interactions can be used to refine docking predictions and to detect macro-characteristics, such as the binding funnel. A new GRAMM web server for protein docking predicts a spectrum of docking poses that characterize the intermolecular energy landscape in protein interaction. A user-friendly interface provides options to choose free or template-based docking, as well as other advanced features, such as clustering of the docking poses, and interactive visualization of the docked models.