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Age-related macular degeneration (AMD) is one of the leading causes of visual loss in older patients. No effective drug is available for this pathology, but studies about therapy with stem cells replacing the damaged retinal cells with retinal pigment epithelium (RPE) were described. The documentation of AMD progression and the response to stem cell therapy have been performed by optical coherence tomography, microperimetry, and other diagnostic technologies. This chapter reports a clinical review of the most important clinical trials and protocols regarding the use of stem cells in AMD.

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Atrophic Macular Degeneration and Stem Cell Therapy: A Clinical Review

  • 章节

  • 发表日期：

    2024年

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  • Silvia Babighian,
  • Maria Sole Zanella,
  • Irene Gattazzo,
  • Alessandro Galan,
  • Caterina Gagliano,
  • Fabiana D’Esposito,
  • Marco Zeppieri

摘要

Age-related macular degeneration (AMD) is one of the leading causes of visual loss in older patients. No effective drug is available for this pathology, but studies about therapy with stem cells replacing the damaged retinal cells with retinal pigment epithelium (RPE) were described. The documentation of AMD progression and the response to stem cell therapy have been performed by optical coherence tomography, microperimetry, and other diagnostic technologies. This chapter reports a clinical review of the most important clinical trials and protocols regarding the use of stem cells in AMD.