Tandem Multicomponent Reactions for Diverse Heterocycles Synthesis Under 3d-Transition Metal Catalysis

The synthesis of heterocycles from renewable starting materials is a desirable goal for chemical research, as heterocycles have many applications in pharmaceuticals, material chemistry, and natural products. Recently, there has been a notable focus on utilizing earth-abundant 3d-transition-metal catalysts in contemporary catalysis, serving as a viable alternative to noble metals. This chapter provides an in-depth discussion of the recent advancements in 3d-transition metal-catalyzed acceptorless dehydrogenative coupling (ADC) reactions for the construction of diverse heterocyclic compounds. These reactions offer an efficient and environmentally friendly approach to the synthesis of valuable heterocyclic compounds.