Bone Metastasis 1: The Spine
摘要
Vertebral metastases are the most common malignant lesions of the spine, frequently originating from primary tumors of the breast, lung, prostate, thyroid, kidney, and liver. Imaging plays a central role in the diagnosis, staging, and monitoring of these lesions. Conventional radiographs, though widely accessible, have limited sensitivity and typically detect metastases only after substantial bone loss has occurred. Metastases may appear as lytic, sclerotic, or mixed lesions. Cross-sectional imaging modalities offer detailed anatomical information. CT is particularly useful in identifying cortical destruction, pedicle erosion, and vertebral collapse, while MRI is superior in evaluating soft tissue involvement, spinal cord compression, and marrow infiltration. Malignant vertebral collapse often presents with cortical disruption, epidural or paravertebral soft tissue masses, and marked loss of vertebral body height with convex bulging. Interventional radiology contributes to both diagnosis and treatment through procedures like image-guided biopsy, vertebroplasty or kyphoplasty, tumor ablation, and embolization. Emerging applications of AI are enhancing detection, segmentation, and treatment planning.