Lead-free perovskites (LFPs) have garnered significant attention for light-harvesting applications and environmental remediation such as solar energy conversion, water splitting, pollutant degradation, and more recently photocatalysis for organic transformations. This chapter provides a comprehensive overview of the development status of LFPs and related materials with potential photocatalytic activity in the synthesis of valuable chemicals as final product. The ongoing research in organic reactions including C–C and C–X heteroatom bond formation, amine oxidative coupling, selective alcohol oxidation, and toluene oxidation, among others, and the reaction mechanisms will be summarized. Furthermore, the future perspective and remaining challenge in this attractive research topic in organic chemistry and the most promising developing strategies for the design of advanced lead-free halide perovskite photocatalysts for photoredox reactions will be presented.