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This chapter explores the transformative role of metal-based compounds in diverse cancer treatment strategies. Metal complexes enhance immunotherapy by modulating immune responses and also synergize with conventional treatments in combination therapy. In non-invasive modalities like photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT), metal complexes act as potent agents, generating reactive oxygen species (ROS), or heat, for targeted tumour destruction. Metallic nanoparticles and metal-organic framework (MOFs) offer innovative approaches, enhancing drug delivery and therapeutic effects. Metal-based compounds also reveal promising targets, disrupting key cellular processes. With their unique properties, these compounds signify a paradigm shift, promising improved outcomes and a new era of hope in cancer treatment.

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Advances in Metal-Based Compounds as Emerging Therapeutics for Cancer Treatment

  • 章节

  • 发表日期：

    2024年

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  • May Lee Low,
  • Chun-Wai Mai,
  • Swee Pin Yeap,
  • Yoon Yee Then,
  • Mogana Sundari Rajagopal,
  • Saad Tayyab

摘要

This chapter explores the transformative role of metal-based compounds in diverse cancer treatment strategies. Metal complexes enhance immunotherapy by modulating immune responses and also synergize with conventional treatments in combination therapy. In non-invasive modalities like photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT), metal complexes act as potent agents, generating reactive oxygen species (ROS), or heat, for targeted tumour destruction. Metallic nanoparticles and metal-organic framework (MOFs) offer innovative approaches, enhancing drug delivery and therapeutic effects. Metal-based compounds also reveal promising targets, disrupting key cellular processes. With their unique properties, these compounds signify a paradigm shift, promising improved outcomes and a new era of hope in cancer treatment.