Microbial strains, communities, and enzymes process side-streams into valuable products in a microbiological biorefinery. Proactive engineering and manufacturing of related bioreactors and other equipment is crucial. Production processes should be engineered in a seamless collaboration, so that the equipment optimally supports the biorefinery’s function. This chapter presents various ways to educate microbiological biorefinery principles and operations for professionals. This education can occur in the classroom and hands-on, in biorefinery pilots, laboratories or purification plants.