<p>The Handbook of Tissue Reconstruction and Regeneration provides up-to-date insights into emerging topics (both from a surgical perspective and from a material perspective) that will ultimately contribute to improved outcomes and/or better treatment options for patients with damaged or diseased soft and hard tissues. The handbook dissects the latest surgical, biomaterials, and biofabrication innovations and imparts greater knowledge for surgeons, medical students, and clinicians into ways we can repair and reconstruct damaged tissues leading to quicker recovery for patients. The handbook is divided into several sections covering areas such as craniofacial reconstruction, orthopedics, soft tissue repair, post-operative rehabilitation, and emerging technologies such as artificial intelligence (AI), robotic surgery, and mixed reality, all of which are vital to advancing our understanding into how we can repair the human body. Edited and written by internationally recognized surgeons and experts from various medical specialties, the handbook provides in-depth explanation into surgical basics and procedures along with medical observations as well as reviewing the clinical performance of biomaterials used in tissue repair and reconstruction. In addition, the handbook discusses the clinical utilization of AI and the legal, ethical, and regulatory challenges associated with it. This provides medical professionals the necessary know-hows into ways they can employ AI. Furthermore, the handbook examines the use of virtual and augmented reality in areas such as surgical planning and during post-operative rehabilitation. This handbook is intended for readers such as medical students and researchers, healthcare professionals, university and hospital-based clinicians, and practicing doctors and surgeons, who are interested in the latest surgical techniques and developing innovations in tissue reconstruction and regeneration.</p>