<p><span class="TextRun SCXW191933820 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW191933820 BCX0">Th</span><span class="NormalTextRun SCXW191933820 BCX0">is book covers up-to-date knowledge of how designs found in nature use tissue hierarchies to achiev</span><span class="NormalTextRun SCXW191933820 BCX0">e </span><span class="NormalTextRun SCXW191933820 BCX0">optim</span><span class="NormalTextRun SCXW191933820 BCX0">al</span><span class="NormalTextRun SCXW191933820 BCX0"> functions, and how these principles are applied in bioengineering. </span><span class="NormalTextRun SCXW191933820 BCX0">The </span><span class="NormalTextRun SCXW191933820 BCX0">hierarchy-based multiscale approach has the potential to drive novel biomaterial designs, advance tissu</span><span class="NormalTextRun SCXW191933820 BCX0">e e</span><span class="NormalTextRun SCXW191933820 BCX0">ngin</span><span class="NormalTextRun SCXW191933820 BCX0">eering a</span><span class="NormalTextRun SCXW191933820 BCX0">nd regeneration, </span><span class="NormalTextRun SCXW191933820 BCX0">as</span><span class="NormalTextRun SCXW191933820 BCX0">sist</span><span class="NormalTextRun SCXW191933820 BCX0"> i</span><span class="NormalTextRun SCXW191933820 BCX0">n tissue-function integration, improve high-fidelity computational modeling aided by machine learning, and enhance the development of innovative characterization tools and methodologies.</span> <span class="NormalTextRun SCXW191933820 BCX0">T</span><span class="NormalTextRun SCXW191933820 BCX0">his book present</span><span class="NormalTextRun SCXW191933820 BCX0">s</span> <span class="NormalTextRun SCXW191933820 BCX0">the latest high-impact research achievements in bioengineered and natural hierarchical systems within a clinical context. Our aim is two-fold: (</span><span class="NormalTextRun SpellingErrorV2Themed SCXW191933820 BCX0">i</span><span class="NormalTextRun SCXW191933820 BCX0">)</span> <span class="NormalTextRun SCXW191933820 BCX0">to emphasize the importance of integrating and bridging bioengineering designs at various tissue hierarchical levels and (ii) to foster dialogue and collaboration among bioengineers, </span><span class="NormalTextRun SpellingErrorV2Themed SCXW191933820 BCX0">bi</span><span class="NormalTextRun SpellingErrorV2Themed SCXW191933820 BCX0">omechanists</span><span class="NormalTextRun SCXW191933820 BCX0">, </span><span class="NormalTextRun SCXW191933820 BCX0">and clinicians.</span></span><span class="EOP SCXW191933820 BCX0" data-ccp-props="{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}">&#xa0;</span></p>

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Integration and Bridging of Multiscale Bioengineering Designs and Tissue Biomechanics

摘要

This book covers up-to-date knowledge of how designs found in nature use tissue hierarchies to achieve optimal functions, and how these principles are applied in bioengineering. The hierarchy-based multiscale approach has the potential to drive novel biomaterial designs, advance tissue engineering and regeneration, assist in tissue-function integration, improve high-fidelity computational modeling aided by machine learning, and enhance the development of innovative characterization tools and methodologies. This book presents the latest high-impact research achievements in bioengineered and natural hierarchical systems within a clinical context. Our aim is two-fold: (i) to emphasize the importance of integrating and bridging bioengineering designs at various tissue hierarchical levels and (ii) to foster dialogue and collaboration among bioengineers, biomechanists, and clinicians.