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<p><span style="font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: Aptos; mso-fareast-theme-font: minor-latin; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">This fully updated edition presents a </span><span lang="EN-CA" style="font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: Aptos; mso-fareast-theme-font: minor-latin; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">collection of protocols reflecting the latest advancements in exon skipping and inclusion strategies. The book explores the design of </span><span style="font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 0pt; mso-ligatures: none; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">antisense oligonucleotide therapies, in vitro and in vivo evaluation of exon skipping in </span><span lang="EN-CA" style="font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 0pt; mso-ligatures: none; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">Duchenne muscular dystrophy, enhancing exon skipping efficiency, as well as methods involving spinal muscular atrophy and other diseases. Written for the highly successful <em>Methods in Molecular Biology </em>series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. </span></p><p>&#xa0;</p><p><span lang="EN-CA" style="font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 0pt; mso-ligatures: none; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">Authoritative and comprehensive, <em>Exon Skipping and Inclusion Therapies: Methods and Protocols, Second Edition</em> serves as a valuable resource for scientists working to refine RNA-targeted therapeutics and translate them into clinical applications.</span></p>

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Exon Skipping and Inclusion Therapies

  • 书籍

  • 发表日期：

    2025年

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摘要

This fully updated edition presents a collection of protocols reflecting the latest advancements in exon skipping and inclusion strategies. The book explores the design of antisense oligonucleotide therapies, in vitro and in vivo evaluation of exon skipping in Duchenne muscular dystrophy, enhancing exon skipping efficiency, as well as methods involving spinal muscular atrophy and other diseases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and comprehensive, Exon Skipping and Inclusion Therapies: Methods and Protocols, Second Edition serves as a valuable resource for scientists working to refine RNA-targeted therapeutics and translate them into clinical applications.