<p class="MsoNormal" style="margin-bottom: 0in; line-height: 150%; background: white;"><span lang="EN-GB" style="font-size: 12.0pt; line-height: 150%; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: Calibri; color: #414042; mso-ansi-language: EN-GB; mso-fareast-language: EL;">This volume explores a collection of the most recent experimental approaches for the detection,&#xa0;</span><span lang="EN-GB" style="font-size: 12.0pt; line-height: 150%; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: Calibri; mso-ansi-language: EN-GB; mso-fareast-language: EL;">modelling<span style="color: #414042;">, characterization, and in-depth computational analysis of the biological phenomenon known as Oncogene-Induced Senescence (OIS). The chapters in this book cover topics such as protocols to study OIS in two-dimensional, three-dimensional, and <span style="mso-bidi-font-style: italic;">in vivo</span> (animal and human) setting</span>s<span style="color: #414042;">; analyzing OIS using high-throughput bioinformatics; and discriminate OIS from aging. Published in the highly successful&#xa0;<em>Methods in Molecular Biology</em> series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting to avoid known pitfalls.<br><br></br></br></span></span><span lang="EN-GB" style="font-size: 12.0pt; line-height: 150%; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: Calibri; color: #414042; mso-ansi-language: EN-GB; mso-fareast-language: EL;">Comprehensive and authoritative,&#xa0;<em>Oncogene-Induced Senescence: Methods and Protocols&#xa0;</em>is a valuable resource for basic researchers and clinicians in the oncology field, and a great guide for computational scientists.</span></p>

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Oncogene-Induced Senescence

摘要

This volume explores a collection of the most recent experimental approaches for the detection, modelling, characterization, and in-depth computational analysis of the biological phenomenon known as Oncogene-Induced Senescence (OIS). The chapters in this book cover topics such as protocols to study OIS in two-dimensional, three-dimensional, and in vivo (animal and human) settings; analyzing OIS using high-throughput bioinformatics; and discriminate OIS from aging. Published in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting to avoid known pitfalls.



Comprehensive and authoritative, Oncogene-Induced Senescence: Methods and Protocols is a valuable resource for basic researchers and clinicians in the oncology field, and a great guide for computational scientists.