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Abstract <p>The Co-doped ZnO and Co-doped ZnO/CQDs nanoparticles are prepared by the chemical method. The incorporation of CQDs reduces the crystallite size, whereas the bond length remains the same. The chemical composition and elemental mapping are reported. The bandgap of Co-doped ZnO is reduced by the addition of CQDs. The Carbon quantum dots-supported Co-doped ZnO nanoparticles exhibited antibacterial activity against <i>B. subtilis</i>, <i>E. coli</i>, and <i>K. pneumoniae.</i> Both samples exhibited an increase in antioxidant activity with the increase in concentration and the IC50 value was found to be 56.57 and 67.3 μg/mL for Co-doped ZnO/CQDs and Co-doped ZnO nanoparticles, respectively. The concentration-dependent decrease in cell viability with the visible morphological deterioration indicating cell death was observed in lung adenocarcinoma cells when treated with Co-doped and Co-doped ZnO/CQD with the IC50 value of 58.833 and 55.046 µg/mL, respectively.</p>

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Investigation of Structural, Antibacterial, Antioxidant, and Anticancer Properties of Carbon Quantum Dot Supported Co-doped ZnO Nanoparticles

  • 期刊论文

  • 发表日期：

    2026年1月1日

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  • A. Janaki,
  • L. Bruno Chandrasekar,
  • M. Karunakaran,
  • T. Sathis Kumar,
  • M. Anusha,
  • M. Divya Gnaneswari,
  • E. Lavanya,
  • P. Shunmuga Sundaram,
  • Sonaimuthu Mohandoss,
  • J. Thirumalai

摘要

Abstract

The Co-doped ZnO and Co-doped ZnO/CQDs nanoparticles are prepared by the chemical method. The incorporation of CQDs reduces the crystallite size, whereas the bond length remains the same. The chemical composition and elemental mapping are reported. The bandgap of Co-doped ZnO is reduced by the addition of CQDs. The Carbon quantum dots-supported Co-doped ZnO nanoparticles exhibited antibacterial activity against B. subtilis, E. coli, and K. pneumoniae. Both samples exhibited an increase in antioxidant activity with the increase in concentration and the IC50 value was found to be 56.57 and 67.3 μg/mL for Co-doped ZnO/CQDs and Co-doped ZnO nanoparticles, respectively. The concentration-dependent decrease in cell viability with the visible morphological deterioration indicating cell death was observed in lung adenocarcinoma cells when treated with Co-doped and Co-doped ZnO/CQD with the IC50 value of 58.833 and 55.046 µg/mL, respectively.