A Review of COVID-19 Effective Pharmaceutics Based on Molecular Targets and Single Nucleotide Polymorphisms

COVID-19 is a highly contagious viral disorder which declared a global pandemic and results in more than 6 million mortalities worldwide since the late December 2019. Given that it remains a major health issue, finding the best treatments to counteract the effects of COVID-19 is critical, and numerous drugs are suggested and employed in clinical trials against COVID-19. Based on currently disseminated scientific documents, this review article gave a summary of prospective therapies in the management of COVID-19. We presented a comprehensive description of their molecular mechanisms and demonstrated the function of the target cells in COVID-19 virus infection after categorizing pharmaceutics into anti-interleukin drugs, Janus kinase inhibitors, antiviral factors, monoclonal antibodies, corticosteroids, and anticoagulant drugs. Furthermore, we examined the single nucleotide polymorphisms that may interact with the functioning of these medications. The goal of this review was to provide beneficial therapy medications to COVID-19 patients and introduce single nucleotide polymorphisms affecting them. We hope that this Review shines light on the field of current COVID-19 research, raises awareness, and assists researchers in selecting the best COVID-19 therapy regimens.