Abstract <p>The results of studies of the response of the soil layer to seismic impacts in the cryolithozone for frozen and thawed soils and their combinations are presented. Based on the research results, changes in seismic properties in the frozen soil massif have been analyzed and the effect of these changes on the amplitude-frequency level of seismic shaking during an earthquake has been estimated. For various variants of seismogeological models, changes in the seismic effect under the effect of high-frequency and low-frequency signals have been estimated based on mathematical modeling. It has been shown that the seismic response level of the cryolithozone soil massif containing the talik zone is determined by its location in the permafrost massif, as well as the ratio of the thicknesses of the thawed and frozen layers. The results of numerical modeling allow a reasonable approach to solving seismic microzoning problems for estimating and predicting seismic conditions in areas with a complex engineering-geocryological structure.</p>