Abstract <p>The study of pore water composition is an effective diagnostic tool to understand and interpret the physical and chemical processes during water–rock interaction. The correct choice of the laboratory extraction method directly determines the quality of the results of interpretation of its chemical composition. The paper reviews the leading modern methods of pore water extraction from low-permeability deposits: centrifugation, Rhizon samplers, and high-pressure squeezing, as well as indirect method of water extraction and method of viscous fluid displacement. The paper presents a number of advantages and disadvantages of these methods and characterizes their effectiveness for low-permeability rocks with different levels of water saturation and different properties.</p>