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Study of Modified Hodgkin–Huxley Model in the Presence of Stimulation and Random Noise

  • V. V. Aleksandrov,
  • I. A. Kozik,
  • Yu. S. Semenov

摘要

Abstract

In the paper we continue the research on the modified Hodgkin–Huxley model in the presence of random noise. It is shown that, adding a certain short-time stimulation current, a random noise of low amplitude does not prevent the system transition from the motion within a neighborhood of the small stable limit cycle (the mode ‘‘None’’ in accordance with the principal neurophysiological ‘‘All or none’’-law) to the motion along the big stable limit cycle called ‘‘duck nose’’ (the mode ‘‘All’’ respectively). At the same time, the high amplitude random noise can yield a series of transitions from one regime to the other and vice versa, even for a short-time stimulation. In the absence of stimulation and in the presence of high amplitude noise, such series of transitions were observed earlier during computer simulation.