Scholarlink

Abstract <p>Comparative immunofluorescence analysis of TUBB3 expression in primary and metastatic tissues from transplanted mouse tumors demonstrates a marked increase in both the level and intensity of TUBB3 expression in highly metastatic Lewis lung carcinoma, relative to the less metastatic LC-67 tumor. These in vivo findings give experimental evidence that the tumor-associated protein TUBB3 contributes to metastatic potential and underscore its relevance as a prognostic marker of tumor aggressiveness.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Experimental In Vivo Evidence of the Prognostic Significance of Beta-III Tubulin (TUBB3) as a Molecular Marker of Tumor Metastatic Aggressiveness

  • 期刊论文

  • 发表日期：

    2025年9月4日

查看全文
  • A. N. Grishanina,
  • T. A. Bogush,
  • S. A. Kaliuzhny,
  • A. M. Scherbakov,
  • E. A. Bogush,
  • M. Ya. Melnikov,
  • V. S. Kosorukov

摘要

Abstract

Comparative immunofluorescence analysis of TUBB3 expression in primary and metastatic tissues from transplanted mouse tumors demonstrates a marked increase in both the level and intensity of TUBB3 expression in highly metastatic Lewis lung carcinoma, relative to the less metastatic LC-67 tumor. These in vivo findings give experimental evidence that the tumor-associated protein TUBB3 contributes to metastatic potential and underscore its relevance as a prognostic marker of tumor aggressiveness.