<p>An approach is considered to the use of digital twins, including human digital twins, as part of socio-cyber-physical systems. The analysis of existing approaches to the construction of digital twins and digital twin systems is carried out. Possible approaches to building digital twin of a human, as well as a collective or group of people, who are presented as elements of socio-cyber-physical system, are analyzed. It is proposed to use a multilevel polymodel as a model. A generalized model of socio-cyber-physical system based on digital twins, an ontological model and a generalized structure of human digital twin are presented. An example of using the developed approach in the university’s educational process using competence models is given.</p>