<p>The corrosive effects of acid rain have a profound impact on the construction of underground tunnels, the extraction of water hydrocarbon compounds, resource development, and the long-term preservation of stone cultural artifacts. A hydro-chemo-mechanical constitutive modeling of cemented granular materials was developed using the Drucker-Prager strength criterion and the Weibull distribution as a basis. Three components of the granular material during chemical corrosion were focused on: depositional bond (DP) dissolution, diagenetic bond (DG) dissolution and grain dissolution. Under acidic conditions, the specimens exhibited progressively greater chemical damage with decreasing pH. Conversely, in alkaline solutions, damage progression was mitigated by the formation of new reaction products that filled surface fissures and pores. The chemical factor (<i>D</i>_c) was determined by considering the initial concentration and time of hydrogen and hydroxide ions. The degree of acidic damage or alkaline enhancement was obtained by calculating the chemical variables for chemical aqueous solutions at pH 3, 5, 7, 9 and 11, and the data showed that the acidic solution at pH 3 had the highest degree of deterioration. In addition, the constitutive model was compared with experimental data obtained by earlier researchers. The results show that the stress–strain behaviour of cemented granular materials, particularly sandstones, under different pH and peritectic conditions can be predicted by using a hydro-chemo-mechanical constitutive model incorporating chemical factors. This theoretical framework provides a valuable reference for geotechnical engineering in the presence of chemical corrosion.</p>