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<p>There are various materials that have been used and studied for use in tissue engineering, mainly natural polymers, synthetics and ceramic materials. These materials must have biocompatibility, biodegradability, osteoconductivity, among others. Therefore, in this work a magnetic hybrid scaffold was manufactured from chitosan, hydroxyapatite nanoparticles&#xa0;(nHA) and magnetic nanoparticles&#xa0;(MNP) in order to perform future tests of proliferation of periodontal tissue cells. nHA were used, which were synthesized by the hydrothermal method obtaining nanorods morphology and a size of 20–30 nm, the magnetic nanoparticles MNP were synthesized by the co-precipitation method and obtained in a size range of 12–14 nm with spherical morphology. A material with magnetic saturation of 9 emu/g was obtained and in the crystalline structure it is observed that the structure of the hydroxyapatite nanoparticles predominates.</p> Graphical Abstract <p></p>

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Physicochemical properties of magnetic scaffolds with hydroxyapatite nanoparticles and chitosan

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月3日

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  • Dulce Araceli Guzman-Rocha,
  • Mario Eduardo Cano-Gonzalez,
  • Rene Garcia-Contreras

摘要

There are various materials that have been used and studied for use in tissue engineering, mainly natural polymers, synthetics and ceramic materials. These materials must have biocompatibility, biodegradability, osteoconductivity, among others. Therefore, in this work a magnetic hybrid scaffold was manufactured from chitosan, hydroxyapatite nanoparticles (nHA) and magnetic nanoparticles (MNP) in order to perform future tests of proliferation of periodontal tissue cells. nHA were used, which were synthesized by the hydrothermal method obtaining nanorods morphology and a size of 20–30 nm, the magnetic nanoparticles MNP were synthesized by the co-precipitation method and obtained in a size range of 12–14 nm with spherical morphology. A material with magnetic saturation of 9 emu/g was obtained and in the crystalline structure it is observed that the structure of the hydroxyapatite nanoparticles predominates.

Graphical Abstract