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<p>Bone scaffolds must provide mechanical stability while maintaining an optimized porous structure. In this study, the mechanical performance of polymeric scaffolds designed for additive manufacturing was evaluated using FEM, combined with a multifactorial design. Three-dimensional scaffolds designed from polymers, ABS, PLA UHMWPE, and PEEK, were analyzed considering scaffold length (5–6&#xa0;mm) and pore diameter (0.4–0.8&#xa0;mm) under a compressive load of 750 N. Statistical analysis showed that pore diameter significantly influenced displacement and strain. The regression models exhibited high predictive capability. The configuration of 6&#xa0;mm length and 0.4&#xa0;mm pore diameter provided the highest mechanical stability.</p> Graphical abstract <p></p>

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Design and finite element analysis of polymeric scaffolds for additive manufacturing in bone tissue engineering

  • 期刊论文

  • 发表日期：

    2026年5月12日

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  • M. I. Martínez-Valencia,
  • C. Hernández-Navarro,
  • J. A. Vázquez-López,
  • F. J. Cervantes-Vallejo,
  • J. Muñoz-Saldaña,
  • J. L. Díaz-León,
  • J. Y. Ramos-Martínez

摘要

Bone scaffolds must provide mechanical stability while maintaining an optimized porous structure. In this study, the mechanical performance of polymeric scaffolds designed for additive manufacturing was evaluated using FEM, combined with a multifactorial design. Three-dimensional scaffolds designed from polymers, ABS, PLA UHMWPE, and PEEK, were analyzed considering scaffold length (5–6 mm) and pore diameter (0.4–0.8 mm) under a compressive load of 750 N. Statistical analysis showed that pore diameter significantly influenced displacement and strain. The regression models exhibited high predictive capability. The configuration of 6 mm length and 0.4 mm pore diameter provided the highest mechanical stability.

Graphical abstract