Scholarlink

<p>While the first wave of biomedical nanomaterials provided novel tools for drug delivery, imaging, and diagnostics, the field is undergoing a significant transformation, moving beyond single-purpose nanoparticles toward sophisticated, multi-component nanosystems, including metal–organic frameworks (MOFs), nanofibers, and hybrid surface coatings designed for synergistic action. This perspective review analyzes emerging trends in biomedical engineering, highlighting toward integrating diagnostic, therapeutic, and regenerative functions into unified platforms. Examining recent advances—from MOFs that enhance drug efficacy to functionalized nanofibers that direct cell differentiation—we argue that the future lies in “the system is the solution.” We develop three main themes: (1) Synergistic therapeutics, where nanomaterials act as active partners; (2) Smart bio-interfaces, where structure and surface engineering command biological responses; and (3) The challenge of complexity, which emphasizes the need for advanced characterization and scalable synthesis. This perspective review outlines design principles, structure–function relationships, and key barriers that define next-generation biomedical nanomaterials.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Next-generation nanomaterials for biomedical integration: Synergy, function, and translation

  • 期刊论文

  • 发表日期：

    2025年11月10日

查看全文
  • Rodrigo Savio Pessoa,
  • Jorge Delezuk,
  • Bruno Manzolli,
  • Stephen Saddow,
  • Mariana Amorim Fraga

摘要

While the first wave of biomedical nanomaterials provided novel tools for drug delivery, imaging, and diagnostics, the field is undergoing a significant transformation, moving beyond single-purpose nanoparticles toward sophisticated, multi-component nanosystems, including metal–organic frameworks (MOFs), nanofibers, and hybrid surface coatings designed for synergistic action. This perspective review analyzes emerging trends in biomedical engineering, highlighting toward integrating diagnostic, therapeutic, and regenerative functions into unified platforms. Examining recent advances—from MOFs that enhance drug efficacy to functionalized nanofibers that direct cell differentiation—we argue that the future lies in “the system is the solution.” We develop three main themes: (1) Synergistic therapeutics, where nanomaterials act as active partners; (2) Smart bio-interfaces, where structure and surface engineering command biological responses; and (3) The challenge of complexity, which emphasizes the need for advanced characterization and scalable synthesis. This perspective review outlines design principles, structure–function relationships, and key barriers that define next-generation biomedical nanomaterials.

Graphical Abstract