Total Pancreatectomy for Locally Advanced Pancreatic Adenocarcinoma with Coeliac Trunk Resection and Retrograde Gastric Revascularization Through Aorto-Hepato-Spleno Allograft
摘要
Locally advanced pancreatic adenocarcinomas (LA-PDAC) are more frequently operated now than in the past because of new regimen chemotherapy and improvement in surgical technique.
A 57-year-old male with LA-PDAC at the head–neck junction with circumferential invasion of the CT and the mesentericoportal axis showed excellent response to chemotherapy (FOLFIRINOX, 12 cycles) and radiotherapy (54 Gy) with normalization of tumour markers. One year later, TP instead of PD was decided to avoid postoperative pancreatic fistula.
Venous and arterial liver ischaemia times were 11 min and 31 min, respectively. The postoperative outcome showed asymptomatic pseudoaneurysm on the hepatic anastomosis. Pathology confirmed T1cN1R0. Nine months after surgery, no recurrence was observed.
ConclusionCT resection may be needed during PD. If the right gastric pedicle cannot be preserved, retrograde gastric revascularization through the splenic artery is an important technical modification. The availability of allografts from bank vessels is very useful, and the outcome is mitigated by TP.