Laparoscopic Left Side Duodenum Adenocarcinoma Resection (III–IV Segment): A Step-By-Step Surgical Technique

Nonampullary duodenal adenocarcinoma (NDA) accounts for approximately 5% of all gastrointestinal cancers. Complete surgical resection (R0) with regional draining lymph node removal is mandatory as treatment to potentially cure nonampullary duodenal cancer or to achieve long-term survival.

According to existing literature, minimally invasive surgery has been reported to be safe and oncologically equivalent in pancreaticoduodenectomy for pancreatic and duodenal cancer. We describe a fully laparoscopic approach for the left-side adenocarcinoma of the duodenum “left-side” is defined with reference to the mesenteric vessels (III–IV segment).

For the first time in literature, this multimedia paper describes a fully laparoscopic complete resection (R0) of the left side of the duodenum (III–IV segment) with locoregional lymph node resection. The main steps of the procedure are described using the concept of the critical view of safety. Reconstruction of intestinal continuity was ensured by full intracorporeal anastomosis.

Through the tips and indications presented in this article, we supply a guide to the minimally invasive approach and increase operating surgeons’ familiarity with such a complex procedure.