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Complete Laparoscopic Type C2 Radical Surgery for Cervical Stump Cancer: No-Look and No-Touch Techniques

  • Keyi Zhang,
  • Yue Zhang,
  • Huiyun Wu,
  • Shan Wu,
  • Wenjun Cheng,
  • Chengyan Luo

摘要

Background

Due to previous surgical history and subsequent adhesions between pelvic organs, surgery for cervical stump cancer (CSC) is technically more challenging than surgery for cervical cancer with an intact uterus.1 We aimed to illustrate the related anatomy, surgical steps and techniques of complete laparoscopic type C2 radical surgery (CLRS) for early-stage CSC.

Methods

CLRS for six patients with CSC was performed from January 2021 to January 2022. We demonstrated the detailed skills of parametrial management during CLRS for CSC in case 5 by means of a video. A 58-year-old woman diagnosed with International Federation of Gynecology and Obstetrics (FIGO) 2018 stage IIA1 CSC received CLRS through five operative ports (Fig. 1).

Results

The magnetic resonance imaging (MRI) scans and gross appearance of the specimen are shown in Fig. 2.The median age and body mass index (BMI) of the six patients were 53 years and 23.8, respectively. The median blood loss was 275 mL; the median time of operation was 218 min; the median length of hospitalization was 15 days; and the median time to recover urinary function was 12 days. One patient underwent postoperative radiation for pathologically proven adenocarcinoma with deep stromal invasion,2 while the other five did not. After a median follow-up of 24 months, no patients experienced complications, recurrence, or death (Table 1).

Conclusions

This study details the skills of CLRS for CSC, especially space development and the ‘no-look, no-touch’ tumor-free principle. It is helpful for clinicians to perform safe and standardized surgery on patients with early-stage CSC.

Patient no.

Age at diagnosis (years)

BMI

Reasons for subtotal hysterectomy

FIGO 2018 stage

Histology

Operation

Operation time

(mins)

Blood loss (mL)

Urinary catheter (days)

Hospital stay (days)

Complications

Depth of invasion

LVSI

LNs dissected

TNM stage

Tumor size (mm)

Postoperative radiotherapy

Follow-up (months)

Recurrence

Death

1

50

25.9

Uterine

myoma

IIA1

ASC

CLRS+PLND

221

360

10

12

No

Middle one-third

N

13

T2a1N0M0

16

No

30

No

No

2

55

17.3

Uterine

myoma

IB1

AC

CLRS+PLND

191

270

20

12

No

Deep

one-third

N

24

T1b1N0M0

10

Yes

20

No

No

3

50

24.8

Uterine

myoma

IB1

SC

CLRS+PLND

295

310

13

15

No

Superficial one-third

N

21

T1b1N0M0

15

No

25

No

No

4

63

30.1

Uterine

myoma

IB1

SC

CLRS+PLND

213

180

6

16

No

Superficial one-third

N

25

T1b1N0M0

15

No

19

No

No

5

58

20.2

Postpartum hemorrhage

IIA1

SC

CLRS+PLND

220

100

11

14

No

Middle one-third

N

21

T2a1N0M0

15

No

24

No

No

6

46

22.7

Uterine

myoma

IB1

SC

CLRS+PLND

215

120

14

17

No

Superficial one-third

N

26

T1b1N0M0

12

No

23

No

No

BMI body mass index, FIGO International Federation of Gynecology and Obstetrics, ASC cervical adenosquamous carcinoma, AC cervical adenocarcinoma, SC cervical squamous carcinoma, CLRS+PLND complete laparoscopic radical surgery and pelvic node dissections, LVSI lymphovascular space invasion, N negative, LNs lymph nodes, TNM tumor node metastasis

Table 1

Clinicopathological characteristics, operative details, and outcomes of patients with cervical stump cancer