<p>In this investigation the consequences of a thermophoretic force and Brownian Diffusion on force convection nano fluid (NF) flow above an exponential stretching horizontal flat plate is analysed. The temperature differences between the surface and the surrounding initiate buoyancy force. Mass diffusion process is associated with chemical reaction. The noted aspect of the study is the impact of combined action of force convection and buoyancy. The thermal radiation is also incorporated factor in the temperature distribution. Chemical reaction is incorporated in mass diffusion equation. The fundamental Partial Differential Equations (PDEs) which describe the flows are transformed into Ordinary Differential Equations (ODEs) by employing similarity transformation. Problems are worked out with the help of Keller-Box approach in MATLAB tool. Diagrams are used to identify basic characteristics of fluid component near boundary and bounding surface. The important results pertaining to the flow are tabulated and depicted graphically. The outcomes of current investigation have been found in fair agreement with those already reported and hence could serve as a validation for the problem formulation.</p>