Scholarlink

Background <p>A common sign of lung cancer is central involvement of the airway. Bronchoscopic electrocautery, laser, argon plasma coagulation (APC), cryotherapy, photodynamic therapy, brachytherapy, intra-tumoral chemotherapy, mechanical debridement, and rotational micro-debrider are common treatments for patients with endobronchial neoplasms with the goals of debulking and palliation.</p> Aim <p>To evaluate the safety, feasibility, and usefulness of Bronchoscopic thermal ablation techniques in the management of endobronchial neoplasms.</p> Methods <p>This prospective, interventional, comparative cohort study was conducted in The Chest Department at Kasr Al Ainy Hospital, Cairo University. The study enrolled Forty-Nine patients who were diagnosed with Endobronchial neoplasms. All patients were subjected to a medical history and clinical examination, blood tests (CBC, KFT, LFT, coagulation profile and ABG), and Radiological imaging (Chest x-ray and CT chest). Patients were categorized into three groups according to the bronchoscopic thermal ablation techniques used: group 1(Cryotherapy), group 2 (electrocautery) and group 3(Argon plasma coagulation).</p> Results <p>Males represented 67.35%, and Smokers represented 85.71% of the included patients. Respectively, all three techniques showed significant improvement in the degree of obstruction and relief of clinical symptoms (cough, dyspnea, and hemoptysis) post procedure. The of the procedure duration was the shortest in electrocautery compared to other procedures. Bleeding was the most frequently reported with cryotherapy, while bronchial perforation, pneumothorax and pneumomediastinum were more common in the electrocautery and APC groups.</p> Conclusion <p>Bronchoscopic cryotherapy, electrocautery and Argon plasma coagulation are effective ablation techniques for treating endobronchial lesions. They play an important role in the palliative care of malignant central airway lesions.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Safety, feasibility, and usefulness of bronchoscopic thermal ablation techniques in the management of endobronchial neoplasms

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月16日

查看全文
  • Sabah Ahmed Hussein,
  • Alaa Eldin Omar Shalaby,
  • Raef Hosny Emam,
  • Irene Mohamed Sabry,
  • Hamza Saeed AbdElaziz,
  • Nasser Keshar Abdulnaby

摘要

Background

A common sign of lung cancer is central involvement of the airway. Bronchoscopic electrocautery, laser, argon plasma coagulation (APC), cryotherapy, photodynamic therapy, brachytherapy, intra-tumoral chemotherapy, mechanical debridement, and rotational micro-debrider are common treatments for patients with endobronchial neoplasms with the goals of debulking and palliation.

Aim

To evaluate the safety, feasibility, and usefulness of Bronchoscopic thermal ablation techniques in the management of endobronchial neoplasms.

Methods

This prospective, interventional, comparative cohort study was conducted in The Chest Department at Kasr Al Ainy Hospital, Cairo University. The study enrolled Forty-Nine patients who were diagnosed with Endobronchial neoplasms. All patients were subjected to a medical history and clinical examination, blood tests (CBC, KFT, LFT, coagulation profile and ABG), and Radiological imaging (Chest x-ray and CT chest). Patients were categorized into three groups according to the bronchoscopic thermal ablation techniques used: group 1(Cryotherapy), group 2 (electrocautery) and group 3(Argon plasma coagulation).

Results

Males represented 67.35%, and Smokers represented 85.71% of the included patients. Respectively, all three techniques showed significant improvement in the degree of obstruction and relief of clinical symptoms (cough, dyspnea, and hemoptysis) post procedure. The of the procedure duration was the shortest in electrocautery compared to other procedures. Bleeding was the most frequently reported with cryotherapy, while bronchial perforation, pneumothorax and pneumomediastinum were more common in the electrocautery and APC groups.

Conclusion

Bronchoscopic cryotherapy, electrocautery and Argon plasma coagulation are effective ablation techniques for treating endobronchial lesions. They play an important role in the palliative care of malignant central airway lesions.